EPA-537.1 Analytical Method
Detect and quantify PFAS with mixtures certified and prepared by Wellington for EPA Method 537.1.To fully support the application of EPA-537.1, Wellington has developed solutions and mixtures of native and labelled PFAS, specifically designed for this method.
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Our mixtures are developed in accordance with EPA Method 537.1
These mixtures are designed to meet the analytical requirements of the method, improving the accuracy and sensitivity of the measurements.
All our CRMs are available in 1.2 mL in methanol and are ISO 9001, ISO/IEC 17025 and ISO 17034 certified.
Solution of isotopically mass-labelled substitution standards
Labelled isotope standards
Native standards at 2000 ng/mL: linear isomers
Native standards at 2000 ng/mL: linear and branched isomers
The most comprehensive with additional native standards: PFOA and PFNA isomers
Our commitments
High precision
These innovative solutions enable reliable identification and quantification of target compounds thanks to their exceptional purity and optimum compatibility with analytical protocols.
Designed to meet the rigorous demands of laboratories, our mixtures offer unrivalled analytical performance, ensuring reproducible results that comply with the most stringent regulatory standards. With Wellington, you benefit from reference tools for carrying out cutting-edge environmental analyses.
Certified reliability
Each batch is accompanied by a detailed certificate of analysis, attesting to the quality and purity of the compounds.
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France and Belgium.
Do you have a question? Contact us using the contact form. We will be delighted to advise you.
EPA-537ss-R1 mixture
EPA Method 537.1 Surrogate Primary Dilution Standard (SUR PDS)
1.2 mL, methanol
The EPA-537SS-R1 mixture is a solution of isotopically-labelled substitution standards used for the analysis of PFAS in drinking water according to EPA method 537.1. These standards are used as internal references to correct analytical variations and guarantee accurate quantification of the target analytes using liquid chromatography coupled with mass spectrometry (LC-MS/MS).
List of compounds
| Compound | Acronym | Concentration (ng/mL) |
|---|---|---|
| Perfluoro-n-(1,2-13C2)hexanoic acid | MPFHxA | 1000 |
| Perfluoro-n-(1,2-13C2)decanoic acid | MPFDA | 1000 |
| 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)(13C3)propanoic acid | M3HFPO-DA | 1000 |
| N-ethyl-d5-perfluoro-1-octanesulfonamidoacetic acid | d5-N-EtFOSAA | 4000 |
EPA-537IS mixture
EPA Method 537.1 Internal Standard Primary Dilution Standard (IS PDS)
1.2 mL, methanol
The EPA-537IS mixture developed by Wellington is a solution of isotopic standards used for the analysis of per- and polyfluoroalkylated substances (PFAS) in drinking water, in accordance with EPA method 537. It contains labelled isotopes of specific PFAS compounds, enabling accurate and reliable quantification by liquid chromatography-mass spectrometry (LC-MS/MS).
List of compounds
| Compound | Acronym | Concentration (ng/mL) |
|---|---|---|
| Perfluoro-n-(1,2-13C2)octanoic acid | M2PFOA | 1000 |
| N-methyl-d3-perfluoro-1-octanesulfonamidoacetic acid | d3-N-MeFOSAA | 4000 |
| Sodium perfluoro-1-(1,2,3,4-13C4)octanesulfonate | MPFOS | 3000* |
*The concentration indicated is reported in salt form.
EPA-537PDSL-R1 mixture
EPA Method 537.1 Analyte Primary Dilution Standard (linear isomers only)
1.2 mL, methanol
Wellington’s EPA-537PDSL-R1 mixture is an extended native standards solution for the analysis of per- and polyfluoroalkyl substances (PFAS) in drinking water in accordance with EPA Method 537. It contains an extended panel of unlabelled PFAS, allowing wider analytical coverage for environmental studies by LC-MS/MS.
- Type of compounds: native linear PFAS only
- 9 linear PFCAs (C6-C14).
- 3 linear sulfonates (L-PFBS, L-PFHxS, L-PFOS).
- 2 linear sulfonamidoacetics (N-MeFOSAA, N-EtFOSAA).
- HFPO-DA, NaDONA, 9Cl-PF3ONS, 11Cl-PF3OUdS.
List of compounds
| Compound | Acronym | Concentration (ng/mL) | |
|---|---|---|---|
| Perfluoro-n-hexanoic acid | PFHxA | 2000 | |
| Perfluoro-n-heptanoic acid | PFHpA | 2000 | |
| Perfluoro-n-octanoic acid | PFOA | 2000 | |
| Perfluoro-n-nonanoic acid | PFNA | 2000 | |
| Perfluoro-n-decanoic acid | PFDA | 2000 | |
| Perfluoro-n-undecanoic acid | PFUdA | 2000 | |
| Perfluoro-n-dodecanoic acid | PFDoA | 2000 | |
| Perfluoro-n-tridecanoic acid | PFTrDA | 2000 | |
| Perfluoro-n-tetradecanoic acid | PFTeDA | 2000 | |
| 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid | HFPO-DA | 2000 | |
| N-Methylperfluoro-1-octanesulfonamidoacetic acid | N-MeFOSAA | 2000 | |
| N-Ethylperfluoro-1-octanesulfonamidoacetic acid | N-EtFOSAA | 2000 | |
| Potassium perfluoro-1-butanesulfonate | L-PFBS | 2000* | |
| Sodium perfluoro-1-hexanesulfonate | L-PFHxS | 2000* | |
| Sodium perfluoro-1-octanesulfonate | L-PFOS | 2000* | |
| Sodium dodecafluoro-3H-4,8-dioxanonanoate | NaDONA | 2000* | |
| Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate | 9Cl-PF3ONS | 2000* | |
| Potassium 11-chloroeicosafluoro-3-oxaundecane-1-sulfonate | 11Cl-PF3OUdS | 2000* |
*The concentration indicated is reported in salt form.
EPA-537PDS-R1 mixture
EPA Method 537.1 Analyte Primary Dilution Standard (branched/linear mix)
1.2 mL, methanol
The EPA-537PDS-R1 mixture prepared by Wellington is a solution of native standards designed for the analysis of per- and polyfluoroalkylated substances (PFAS) in drinking water according to EPA method 537. It contains unlabelled PFAS, used as standards for the calibration and quantification of target analytes in liquid chromatography coupled to mass spectrometry (LC-MS/MS).
- Type of compounds: all the native linear PFAS contained in the EPA-537PDSL-R1 mixture, as well as the branched isomers of N-MeFOSAA, N-EtFOSAA, PFHxSK and PFOSK.
List of compounds
*The concentration indicated is reported in salt form.
EPA-537APDS mixture
EPA Method 537.1 Native Analyte Primary Dilution Standard (expanded br/l mix)
1.2 mL, methanol
Wellington’s EPA-537APDS mixture is a solution of additional native standards designed to complement the analysis of PFAS in drinking water according to EPA Method 537.1. It includes additional PFAS compounds not covered by the base mixtures, thus extending the detection and quantification capabilities of LC-MS/MS.
- Type of compounds: all the native linear and branched PFAS contained in the EPA-537PDS-R1 mixture, as well as the branched isomers of PFOA and PFNA.
- Designed to meet EPA recommendations for the integration of branched isomers for improved analytical accuracy.
List of compounds
| Compound | Acronym | Concentration (ng/mL) | |
|---|---|---|---|
| Perfluoro-n-hexanoic acid | PFHxA | 2000 ng/mL | |
| Perfluoro-n-heptanoic acid | PFHpA | 2000 ng/mL | |
| Perfluorooctanoic acid (linear and branched isomers) | br-PFOA | 2000 ng/mL | |
| Perfluorononanoic acid (linear and branched isomers) | br-PFNA | 2000 ng/mL | |
| Perfluoro-n-decanoic acid | PFDA | 2000 ng/mL | |
| Perfluoro-n-undecanoic acid | PFUdA | 2000 ng/mL | |
| Perfluoro-n-dodecanoic acid | PFDoA | 2000 ng/mL | |
| Perfluoro-n-tridecanoic acid | PFTrDA | 2000 ng/mL | |
| Perfluoro-n-tetradecanoic acid | PFTeDA | 2000 ng/mL | |
| 2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoroproproxy)propanoic acid | HFPO-DA | 2000 ng/mL | |
| N-Methylperfluorooctanesulfonamidoacetic acid (linear and branched isomers) | br-NMeFOSAA | 2000 ng/mL | |
| N-Ethylperfluorooctanesulfonamidoacetic acid (linear and branched isomers) | br-NEtFOSAA | 2000 ng/mL | |
| Potassium perfluoro-1-butanesulfonate | L-PFBS | 2000 ng/mL* | |
| Potassium perfluorohexanesulfonate (linear and branched isomers) | br-PFHxSK | 2000 ng/mL* | |
| Potassium perfluorooctanesulfonate (linear and branched isomers) | br-PFOSK | 2000 ng/mL* | |
| Sodium dodecafluoro-3H-4,8-dioxanonanoate | NaDONA | 2000 ng/mL* | |
| Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate | 9Cl-PF3ONS | 2000 ng/mL* | |
| Potassium 11-chloroeicosafluoro-3-oxaundecane-1-sulfonate | 11Cl-PF3OUdS | 2000 ng/mL* |
*The concentration indicated is reported in salt form.
EPA-537.1 SOLUTION/MIXTURES
| Catalogue No. | Description | Unit | Solvent |
|---|---|---|---|
| EPA-537SS-R1 | EPA Method 537 Surrogate Primary Dilution Standard (SUR PDS) | 1.2 mL | methanol |
| EPA-537IS | EPA Method 537 Internal Standard Primary Dilution Standard (IS PDS) | 1.2 mL | methanol |
| EPA-537PDS-R1 | EPA Method 537 Analyte Primary Dilution Standard (branched/linear mix) | 1.2 mL | methanol |
| EPA-537PDSL-R1 | EPA Method 537 Analyte Primary Dilution Standard (linear isomers only) | 1.2 mL | methanol |
| EPA-537APDS | EPA Method 537 Native Analyte Primary Dilution Standard (expanded br/l mix) | 1.2 mL | methanol |
Do you have a question? Contact us using the contact form. We will be delighted to advise you.
PFAS, per- polyfluoroalkyl Substances
Halogenated flame retardants, HFRs and other compounds
Polychlorinated biphenyls, PCBs
Polybrominated diphenyl ethers, PBDEs Polybrominated biphenyls, PBBs
Dioxins, Furans, PCDDs, PCDFs
Organochlorine Pesticides, OCP
Certified reference materials
Other reagents
Find out more about US EPA Method 537.1
EPA Method 537 is an analytical procedure developed by the U.S. Environmental Protection Agency (EPA) for the detection and quantification of per- and polyfluoroalkyl compounds (PFAS) in drinking water. It uses liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) to accurately analyze these contaminants at trace levels.
For more information, see the article EPA Method 537.1: a reference for analysing PFAS in drinking water.
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