ISO 21675:2019 Method

Our solutions for assessing water quality and monitoring persistent pollutants.

To fully support the application of ISO 21675:2019, Wellington has developed solutions and mixtures of native and labelled PFAS, specifically designed for this method.

These mixtures are an essential reference for any environmental monitoring strategy for PFAS.

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Home | Wellington Analytical Standards | PFAS | ISO 21675:2019 Analytical Method

Our Solutions/Mixtures developed for the ISO 21675:2019 method

Controlling PFAS analysis requires appropriate, accurate and validated analytical tools. With its ISO 21675-NSS, ISO 21675-LSS andISO 21675-LSSA mixtures, Wellington Laboratories offers a complete solution, directly compatible with the ISO 21675 standard, and suitable for all stages of analysis: from calibration to advanced quantification.

These mixtures are certified standards designed specifically for the application of the ISO 21675:2019 method, used for the analysis of PFAS (per- and polyfluoroalkylated substances) in water.

The combined use of these 3 mixtures ensures that the ISO 21675:2019 method is applied with maximum analytical rigour.

All our CRMs are available in 1.2 mL in methanol and are ISO 9001, ISO/IEC 17025 and ISO 17034 certified.

Native PFAS standards, targeted analytes in ISO 21675 method.

PFAS-labelled standards, targeted analytes in ISO 21675 method.

Complementary mixture for additional analytes.

Our commitments

Haute précision

Ces solutions innovantes permettent une identification et une quantification fiables des composés cibles grâce à leur pureté exceptionnelle et à leur compatibilité optimale avec les protocoles analytiques.

Conçus pour répondre aux exigences rigoureuses des laboratoires, nos mélanges offrent une performance analytique inégalée, assurant ainsi des résultats reproductibles et conformes aux standards réglementaires les plus stricts. Avec les produits Wellington, vous bénéficiez d’outils de référence pour mener des analyses environnementales de pointe.

Fiabilité certifiée

Chaque lot est accompagné d’un certificat d’analyse détaillé, attestant de la qualité et de la pureté des composés.

Livraison rapide

France et Belgique.

Do you have a question? Contact us using the contact form. We will be delighted to advise you.

Mélange ISO 21675-NSS

ISO 21675:2019 Native Stock Solution

1.2 mL, méthanol

This mixture contains isotopically unlabelled standards of PFAS; analytes targeted in the ISO 21675 method.

    • Composition: a panel of native PFAS substances commonly detected in the environment, such as PFOA, PFOS, PFHxA, PFNA, etc.
    • Example of application: to establish the calibration curve and quantify the analytes.

List of compounds

*The concentration indicated is reported in salt form.

CompoundAcronymConcentration
(ng/mL)
Perfluoro-n-butanoic acidPFBA100
Perfluoro-n-pentanoic acidPFPeA100
Perfluoro-n-hexanoic acidPFHxA100
Perfluoro-n-heptanoic acidPFHpA100
Perfluoro-n-octanoic acidPFOA100
Perfluoro-n-nonanoic acidPFNA100
Perfluoro-n-decanoic acidPFDA100
Perfluoro-n-undecanoic acidPFUdA100
Perfluoro-n-dodecanoic acidPFDoA100
Perfluoro-n-tridecanoic acidPFTrDA100
Perfluoro-n-tetradecanoic acidPFTeDA100
Perfluoro-n-hexadecanoic acidPFHxDA100
Perfluoro-n-octadecanoic acidPFODA100
Perfluoro-1-octanesulfonamideFOSA100
N-Methylperfluoro-1-octanesulfonamideN-MeFOSA100
N-Ethylperfluoro-1-octanesulfonamideN-EtFOSA100
N-Methylperfluoro-1-octanesulfonamidoacetic acidN-MeFOSAA100
N-Ethylperfluoro-1-octanesulfonamidoacetic acidN-EtFOSAA100
2H-Perfluoro-2-decenoic acidFOUEA100
2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acidHFPO-DA100
Potassium perfluoro-1-butanesulfonatePFBS100*
Sodium perfluoro-1-hexanesulfonatePFHxS100*
Sodium perfluoro-1-heptanesulfonatePFHpS100*
Sodium perfluoro-1-octanesulfonatePFOS100*
Sodium perfluoro-1-decanesulfonatePFDS100*
Sodium 1H,1H,2H,2H-perfluorooctanesulfonate6:2FTS100*
Sodium 1H,1H,2H,2H-perfluorodecanesulfonate8:2FTS100*
Sodium dodecafluoro-3H-4,8-dioxanonanoateNaDONA100*
Potassium 9-chlorohexadecafluoro-3-oxanonane-1-sulfonate9Cl-PF3ONS100*
Sodium bis(1H,1H,2H,2H-perfluorodecyl) phosphate8:2diPAP100*

Mélange ISO 21675-LSS

ISO 21675:2019 Labelled Stock Solution

1.2 mL, méthanol

This mixture contains isotopically labelled standards of PFAS, the analytes targeted in the ISO 21675 method.

    • Composition: a range of PFAS identical to those in the NSS mixture, but isotopically labelled.
    • Example of application: as internal references to correct bias, guaranteeing robust and reliable results.

List of compounds

*The concentration indicated is reported in salt form.

CompoundAcronymConcentration
(ng/mL)
Perfluoro-n-(1,2,3,4-13C4)butanoic acidMPFBA100
Perfluoro-n-(1,2,3,4,5-13C5)pentanoic acidM5PFPeA100
Perfluoro-n-(1,2,3,4,6-13C5)hexanoic acidM5PFHxA100
Perfluoro-n-(1,2,3,4-13C4)heptanoic acidM4PFHpA100
Perfluoro-n-(13C8)octanoic acidM8PFOA100
Perfluoro-n-(13C9)nonanoic acidM9PFNA100
Perfluoro-n-(1,2,3,4,5,6-13C6)decanoic acidM6PFDA100
Perfluoro-n-(1,2,3,4,5,6,7-13C7)undecanoic acidM7PFUdA100
Perfluoro-n-(1,2-13C2)dodecanoic acidMPFDoA100
Perfluoro-n-(1,2-13C2)tetradecanoic acidM2PFTeDA100
Perfluoro-n-(1,2-13C2)hexadecanoic acidM2PFHxDA100
Perfluoro-1-(13C8)octanesulfonamideM8FOSA100
N-methyl-d3-perfluoro-1-octanesulfonamided-N-MeFOSA100
N-ethyl-d5-perfluoro-1-octanesulfonamided-N-EtFOSA100
N-methyl-d3-perfluoro-1-octanesulfonamidoacetic acidd3-N-MeFOSAA100
N-ethyl-d5-perfluoro-1-octanesulfonamidoacetic acidd5-N-EtFOSAA100
2H-Perfluoro-(1,2-13C2)-2-decenoic acid (8:2)MFOUEA100
2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)(13C3)propanoic acidM3HFPO-DA100
Sodium perfluoro-1-(2,3,4-13C3)butanesulfonateM3PFBS100*
Sodium perfluoro-1-(1,2,3-13C3)hexanesulfonateM3PFHxS100*
Sodium perfluoro-(13C8)octanesulfonateM8PFOS100*
Sodium 1H,1H,2H,2H-perfluoro(1,2-13C2)octanesulfonate (6:2)M2-6:2FTS100*
Sodium 1H,1H,2H,2H-perfluoro(1,2-13C2)decanesulfonate (8:2)M2-8:2FTS100*
Sodium bis[1H,1H,2H,2H-(1,2-13C2)perfluorodecyl] phosphateM4-8:2diPAP100*

Mélange ISO 21675-LSSA

ISO 21675:2019 Labelled Stock Solution Additional Analytes

1.2 mL, méthanol

ISO 21675-LSSA pfas_wellington_reporter_bcp_may2025

With the ISO 21675-LSSA mixture, Wellington Laboratories provides a targeted response to the needs of analysts faced with the increasing complexity of PFAS in the environment. Added to the main LSS mixture, this solution broadens the spectrum of measurable compounds, while maintaining the rigorous analytical standards imposed by ISO 21675.

List of compounds

*The concentration indicated is reported in salt form.

CompoundAcronymConcentration
(ng/mL)
Perfluoro-n-(1,2-13C2)hexanoic acidMPFHxA100
Perfluoro-n-(1,2,3,4-13C4)octanoic acidMPFOA100
Perfluoro-n-(1,2,3,4,5-13C5)nonanoic acidMPFNA100
Perfluoro-n-(1,2-13C2)decanoic acidMPFDA100
Perfluoro-n-(1,2-13C2)undecanoic acidMPFUdA100
Sodium perfluoro-1-hexane(18O2)sulfonateMPFHxS100*
Sodium perfluoro-1-(1,2,3,4-13C4)octanesulfonateMPFOS100*

Do you have a question? Contact us using the contact form. We will be delighted to advise you.

Wellington Laboratories reagent categories

PFAS, per- polyfluoroalkyl Substances

Halogenated flame retardants, HFRs and other compounds

Polychlorinated biphenyls, PCBs

Polybrominated diphenyl ethers, PBDEs Polybrominated biphenyls, PBBs

PCDDs-PCDFs

Dioxins, Furans, PCDDs, PCDFs

Organochlorine Pesticides, OCP

Certified reference materials

Other reagents

Find out more about the ISO 21675 standard

ISO 21675:2019 specifies a method for the determination of per- and polyfluoroalkylated substances (PFAS) in water, including drinking water, groundwater and surface water. It uses liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) to detect and quantify these contaminants. This method is essential for assessing water quality and monitoring persistent pollutants.

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