{"id":25942,"date":"2024-05-10T06:34:00","date_gmt":"2024-05-10T06:34:00","guid":{"rendered":"https:\/\/bcp-instruments.com\/native-and-13c-labelled-hfpo-da-genx\/"},"modified":"2026-03-26T10:19:51","modified_gmt":"2026-03-26T10:19:51","slug":"native-and-13c-labelled-hfpo-da-genx","status":"publish","type":"post","link":"https:\/\/bcp-instruments.com\/en\/native-and-13c-labelled-hfpo-da-genx\/","title":{"rendered":"Native and 13C-labelled HFPO-DA (GenX)"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h2>Analyse hexafluoropropylene oxide oligomeric acids (HFPO-DA) with our analytical standards<\/h2>\n<p>HFPO-DA, or 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid, is a per- and polyfluoroalkyl (PFAS) compound. Its presence in the environment can result from direct discharges during manufacturing processes or from the leaching of commercial products. <\/p>\n<p>Anticipating concerns about this contamination, in 2013 Wellington Laboratories synthesised native and 13C3-labelled reference standards for HFPO-DA. These standards are essential for researchers carrying out quantitative analyses of this potential contaminant. They are compatible with analytical methods such as liquid chromatography coupled with mass spectrometry (LC-MS), in particular EPA methods 537.1 and 533, which include HFPO-DA among the target analytes.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_id=&#8221;FTS&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Native acid hexafluoropropylene oxide-dimer<br \/>(HFPO-DA [GenX])<\/h3>\n<p>[\/et_pb_text][dvmd_tablepress_styler tbl_id=&#8221;#83&#8243; col_hide=&#8221;1&#8243; row_hide=&#8221;3-4&#8243; ext_row_filtering_mode=&#8221;show&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;4d5c47cc-85a3-4e79-a7b1-d33e00227770&#8243; global_colors_info=&#8221;{}&#8221;][\/dvmd_tablepress_styler][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>13C-labelled acid hexafluoropropylene oxide-dimer: M3HFPO-DA<\/h3>\n<p>[\/et_pb_text][dvmd_tablepress_styler tbl_id=&#8221;#84&#8243; col_hide=&#8221;1&#8243; row_hide=&#8221;3-4&#8243; ext_row_filtering_mode=&#8221;show&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;4d5c47cc-85a3-4e79-a7b1-d33e00227770&#8243; global_colors_info=&#8221;{}&#8221;][\/dvmd_tablepress_styler][et_pb_button button_url=&#8221;https:\/\/well-labs.com\/wellingtoncatalogue2123.html?page=169&#8243; url_new_window=&#8221;on&#8221; button_text=&#8221;See more&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;47a04589-8162-4245-a77b-12d1d293f2b7&#8243; button_bg_color=&#8221;#e5ae19&#8243; button_border_color=&#8221;#e5ae19&#8243; button_border_radius=&#8221;3px&#8221; custom_margin=&#8221;22px|||||&#8221; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221; button_bg_color__hover_enabled=&#8221;on|hover&#8221; button_bg_color__hover=&#8221;#FFFFFF&#8221; button_bg_enable_color__hover=&#8221;on&#8221; button_text_color__hover_enabled=&#8221;on|hover&#8221; button_text_color__hover=&#8221;#e5ae19&#8243; button_border_color__hover_enabled=&#8221;on|hover&#8221; button_border_color__hover=&#8221;#e5ae19&#8243;][\/et_pb_button][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=&#8221;row&#8221; _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>GenX, HFPO-DA (hexafluoropropylene oxide-dimer acid), is a by-product of the manufacture of fluoropolymers, used as a substitute for perfluorooctanoic acids (PFOA) in the manufacture of fluoropolymers, such as Teflon. It is often used in industrial applications for its non-stick and heat-resistant properties. <\/p>\n<p>It can be detected in environmental samples as a result of residual leaks from commercial products or direct releases during manufacturing processes. from commercial products or direct discharges during manufacturing processes.<\/p>\n<h3>The benefits of analytical standards<\/h3>\n<p>Wellington standards for HFPO oligomers allow:<\/p>\n<ul>\n<li>Specific detection by LC-MS\/MS, despite the absence of universal standards for all oligomers.<\/li>\n<li>Reliable quantification using isotopically labelled versions (\u00b9\u00b3C) &#8211; essential in complex matrices.<\/li>\n<\/ul>\n<h3>Contact us<\/h3>\n<p>BCP Instruments can help you with your environmental analyses.<span> <\/span><a href=\"https:\/\/bcp-instruments.com\/en\/home\/wellington-analytical-standards\/pfas-per-polyfluoroalkyl-substances\/genx-hfpo-da-hexafluoropropylene-oxide-dimer-acid\/\" title=\"Contact us today\">Contact us today<\/a><span> <\/span>to find out how our solutions can meet your specific needs.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h3>Find out more:<\/h3>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_4,3_4&#8243; use_custom_gutter=&#8221;on&#8221; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/bcp-instruments.com\/wp-content\/uploads\/2025\/03\/Laboratoires-Wellington-300&#215;137.png&#8221; alt=&#8221;Wellington Laboratories&#8221; title_text=&#8221;Wellington Laboratories&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;80%&#8221; max_width=&#8221;100%&#8221; module_alignment=&#8221;center&#8221; min_height=&#8221;100%&#8221; min_height_tablet=&#8221;100%&#8221; min_height_phone=&#8221;100%&#8221; min_height_last_edited=&#8221;on|tablet&#8221; height=&#8221;100%&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;4.27.2&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;d3172fc8-ec52-49d0-b82c-111dc82dea35&#8243; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<ul>\n<li>Per- and polyfluoroalkylated substances (<span style=\"text-decoration: underline\"><a href=\"https:\/\/bcp-instruments.com\/en\/home\/wellington-analytical-standards\/pfas-per-polyfluoroalkyl-substances\/\" title=\"PFAS\">PFAS<\/a><\/span>)<\/li>\n<li>Hexafluoropropylene oxide oligomeric acids<a href=\"https:\/\/bcp-instruments.com\/en\/home\/wellington-analytical-standards\/pfas-per-polyfluoroalkyl-substances\/genx-hfpo-da-hexafluoropropylene-oxide-dimer-acid\/\" title=\"HFPO-XA\">(HFPO-XA<\/a>)<\/li>\n<li><span style=\"text-decoration: underline\"><a href=\"https:\/\/bcp-instruments.com\/en\/home\/wellington\/\" title=\"Wellington Laboratories\">Wellington Laboratories<\/a><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Analyse hexafluoropropylene oxide oligomeric acids (HFPO-DA) with our analytical standards HFPO-DA, or 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid, is a per- and polyfluoroalkyl (PFAS) compound. Its presence in the environment can result from direct discharges during manufacturing processes or from the leaching of commercial products. Anticipating concerns about this contamination, in 2013 Wellington Laboratories synthesised native and 13C3-labelled reference [&hellip;]<\/p>\n","protected":false},"author":17,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[223],"tags":[260,275],"class_list":["post-25942","post","type-post","status-publish","format-standard","hentry","category-standards-analytiques","tag-pfas","tag-standards-wellington"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Native and 13C-labelled HFPO-DA (GenX) - BCP Instruments<\/title>\n<meta name=\"description\" content=\"HFPO-DA (GenX): Wellington extends its range for the analysis of hexafluoropropylene oxide dimer acids. Discover them now.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/bcp-instruments.com\/en\/native-and-13c-labelled-hfpo-da-genx\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Native and 13C-labelled HFPO-DA (GenX)\" \/>\n<meta property=\"og:description\" content=\"HFPO-DA (GenX): Wellington extends its range for the analysis of hexafluoropropylene oxide dimer acids. 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